Mutations in orthologs of Hps5 result in oculocutaneous albinism in a wide variety of model organisms, including the ruby-eyed 2 phenotype in mice (Zhang et al. 2003), the snow white phenotype in zebrafish (Daly et al. 2013), the pink phenotype in Drosophila (Falcón-Pérez et al. 2007; Syrzycka et al. 2007), and the translucent phenotype in silkworms (Fujii et al. 2012). This evidence concerns the gene HPS5 and oculocutaneous albinism.