Similar results were observed for AktSer473phosphorylation at time points 10, 20 and 40 min upon chemokine stimulation.A similar time course of kinase phosphorylation by CX3CL1 was described formonocytic cells, CX3CR1-transfected HEK293T cells, neuroblastoma and osteoarthritisfibroblasts [19–23]. The gene discussed is CX3CL1; the disease is neuroblastoma.