Finally, ethanol-induced activation and/or dysfunctions in the innate immune/TLR4 response during embryonic/fetal development might have further consequences for immune-related developing organs (e.g., endocrine, liver, gastrointestinal tract and intestinal lymphoid tissues, etc.)by contributing to not only brain dysfunctions but also to other long-lasting pathologies in FASD, such as liver damage [71] and a higher incidence of infections [72, 73], which have been reported in FASD children. The gene discussed is TLR4; the disease is infection.