In addition to individual S11_1, an additional 22 unrelated individuals with SDH germline mutations and evidence of disease (i.e. presence of pheochromocytoma and/or paraganglioma) were assessed for the presence of SDHAF3 c.157 T > C (Additional file 2: Table S1). The gene discussed is SDHAF3; the disease is hereditary pheochromocytoma-paraganglioma.