With regard to clinical variables, 30 (10.1%) subjects’ DAS28-CRP scores were below 2.6, 89 (29.9%) had a RA duration of ≤ 1 year, 120 (40.3%) had anemia, 214 (71.8%) suffered from EMS, and 190 (63.8%) had at least one other chronic disease. This evidence concerns the gene CRP and anemia.