Further adjusting for hypertension, hyperlipidemia, stroke, smoking status, peak CK-MB, any in-hospital revascularization, all four EBMs at discharge as well as diuretics, calcium channel blockers and insulin treatment at discharge, patients with SPC of ≥5.0 mEq/l still were at an increased risk of dying (adjusted HR 1.46, 95% CI 1.03 to 2.07). The gene discussed is INS; the disease is hypertensive disorder.