NFKB1 and neoplasm: Research over the last two decades has consolidated the concept that there is a high correlation between tumor development and inflammation: compounds of the inflammatory tumor microenvironment include leukocytes, cytokines, complement components, and are orchestrated by transcription factors, such as Signal Transducer and Activator of Transcription 3 (STAT3) and nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB)1,.2