In our study, the fatty acid beta oxidation enzymes 17beta-hydroxysteroid dehydrogenase IV and trifunctional enzyme subunit alpha (ECHA) were identified in the ICPL protein and peptide data, and are all increased in T1DM group compared to control group with TIDM/control ratios of 3.03 and 1.59, respectively (S1 Table). This evidence concerns the gene HADHA and type 1 diabetes mellitus.