The pluripotency-associated factors, including SOX2 (SRY box 2), c-MYC (MYC proto-oncogene, bHLH transcription factor), BMI1, NANOG, OCT4 and ABCG2 (ATP-binding cassette subfamily G member G), were upregulated in ZNF687-overexpressing HCC cells (Figure 3g). Here, SOX2 is linked to hepatocellular carcinoma.