ZNF687 was overexpressed in HCC tissues (n=204) but was undetectable in normal liver tissue (n=10), and the HCC specimens contained 0–12.6% ZNF687+ cells, whereas there was no ZNF687 expression in the non-tumor tissues, and ZNF687 was expressed in less than 2% of cells in >70% of the HCC cases (143/204) (Figures 2c and d). This evidence concerns the gene ZNF687 and neoplasm.