The reported risk alleles of genetic variants rs10830963 in MTNR1B and rs10923931 in NOTCH2 were associated with diabetes mellitus type 2-related traits in GWA studies (P<5×10−8) (Zeggini et al., 2008; Prokopenko et al., 2009). This evidence concerns the gene NOTCH2 and type 2 diabetes mellitus.