Using IHC, high level activated NFATc2 expression with intense and widespread nuclear staining were detected in 41 of 102 (40.2%) excised primary NSCLC, while 61 (59.8%) showed low expression with weak nuclear and/or cytoplasmic staining in isolated or small clusters of tumor cells (Figure 1B,C). Here, NFATC2 is linked to neoplasm.