NFATC2 and lung cancer: For functional studies, NFATc2 was silenced by 2 shRNA sequences (shNFATc2-A and -B) in 2 lung cancer cell lines with high basal expression (HCC827, PDCL#24), and ectopically expressed in 2 cell lines with relatively low de novo expression (A549, H1299) (Figure 2D).