MiRNA let-7a down-regulated Myc, and thus reverted the Myc-Induced cell growth in burkitt lymphoma cells (Sampson et al., 2007); miR-34a modulated c-Myc transcriptional complexes, suppressing malignancy in human prostate cancer cells (Yamamura et al., 2012). Here, MYC is linked to Familial prostate cancer.