In addition to miRNA profiling, we also analysed the FOXL2 mutation status of the juvenile-GCT tumours (Additional file 1) and demonstrated that the majority of the juvenile-GCT tumours (5/6) carried the wildtype FOXL2 allele, a finding that is consistent with the high specificity of FOXL2 mutation for adult-GCTs [12–15, 17–20]. This evidence concerns the gene FOXL2 and neoplasm.