The 5-HT2 receptor family (5-HT2A, 5-HT2B and 5-HT2C) has been the focus of much research interest because of its critical role in modulating anxiety-like behavior in animals and humans (Naughton et al., 2000; Graeff, 2002; Wood, 2003; Gordon and Hen, 2004). The gene discussed is HTR2A; the disease is Anxiety.