New genes forautosomal recessive disease include SYNJ1,DNAJC6, VPS13C, and PTRHD1. Deletions ofa region on chromosome 22 (22q11.2del) are also associated with early-onset PD,but the mode of inheritance and the underlying causative gene remain unclear.PODXL mutations were reported in autosomalrecessive PD, but their roles remain to be confirmed. This evidence concerns the gene DNAJC6 and Parkinson disease.