In contrast, BMP-2, BMP-4, BMP-5 and BMP-7 expression has been reported as elevated in breast tumours and the latter two associated with poor prognosis (Bobinac et al. 2005, Raida et al. 2005a, Alarmo et al. 2006, 2007, Davies et al. 2008). The gene discussed is BMP2; the disease is breast neoplasm.