In contrast, BMP-2, BMP-4, BMP-5 and BMP-7 expression has been reported as elevated in breast tumours and the latter two associated with poor prognosis (Bobinac et al. 2005, Raida et al. 2005a, Alarmo et al. 2006, 2007, Davies et al. 2008). This evidence concerns the gene BMP7 and breast neoplasm.