ZEB1 and breast cancer: This effect is also seen with BMP 6, which restores E-cadherin-mediated cell-to-cell adhesion and prevents breast cancer metastasis through the downregulation of miR-21 and δEF1 (ZEB1, whose expression associates with invasive breast cancer phenotype) (Yang et al. 2007, Du et al. 2009, de Boeck et al. 2016).