Independent predictors of stroke were non–insulin‐treated DM (OR: 2.294 [95% CI, 1.130–4.650]; P=0.022), CRF (OR: 3.092 [95% CI, 1.477–6.471]; P=0.003), cardiovascular disease (OR: 1.896 [95% CI, 1.153–3.048; P<0.001), and preoperative cardiovascular disease (OR: 4.074 [95% CI, 1.987–8.355]; P<0.001). The gene discussed is INS; the disease is diabetes mellitus.