Therefore, as part of the Comprehensive Kidney Disease Assessment for Risk Factors, epidemiology, Knowledge, and Attitudes (CKD-AFRiKA) Study [16–18], we conducted a pilot study to: 1) evaluate willingness to participate in genetic research studies among individuals with CKD in an East African setting; 2) demonstrate feasibility of genotyping APOL1 risk alleles G1 and G2 from dried-blood spot samples on filter cards obtained during this field; and 3) assess the frequency of APOL1 risk variants among individuals with CKD from northern Tanzania. The gene discussed is APOL1; the disease is kidney disorder.