Interestingly, HER2/neu positivity was associated with a slightly lower risk of developing metastatic disease for both rs1800795 (AOR 0.45; 95% CI, 0.22–0.94; p = 0.033) (Table 4) and rs4506565 (AOR 0.35; 95% CI, 0.16–0.74; p = 0.006). The gene discussed is ERBB2; the disease is metastatic neoplasm.