FOS and cancer: Our initial studies point to such a possibility as overexpression of EINCR1 leads to decreased expression of a cohort of EGF-induced protein coding genes such as FOS and FOSB. This observation is consistent with the observation that in several human cancer subtypes, EINCR1 is overexpressed, and in the case of lung adenocarcinomas its expression is anti-correlated with the expression of these genes.