Over-expression of MUC1 is common in cancer39 and it is associated with EGFR in epithelial cancers including breast,28, 40 pancreatic,16 endometrial14 and lung.41 Blocking MUC1-C terminal dimerization with a cell-penetrating peptide42 or siRNA silencing MUC1-C expression43 has been shown to suppress EGFR activation-associated cell signalling and survival in non-small cell lung cancer cells. This evidence concerns the gene EGFR and non-small cell lung carcinoma.