We also show that by comparison with a large cohort of 270 lymphomas and B cell subtypes, generally speaking, almost every B-cell lymphoma entity described in the WHO2 corresponds to one group based on 271 NF-κB target genes, thus substantiating a discrimination of these B-cell lymphomas at the transcriptional level. Here, NFKB1 is linked to B-cell non-Hodgkin lymphoma.