As FGF19 expression could be induced by BAs-mediated activation of the FXR, we selected 10 NGT, 9 I-IGT, 10 I-IFG, 12 CGI and 24 T2DM subjects that were matched in terms of sex, age and BMI as a subgroup to investigate profiles of BAs. This evidence concerns the gene FGF19 and type 2 diabetes mellitus.