In addition to the association with type 2 diabetes, one variant (rs174550 (FADS1)) was significantly associated with fasting glucose based on a large-scale meta-analysis of the MAGIC (n = 58.074)15 and two (rs715 (CPS1), rs1136001 (NTAN1)) were significantly associated with BMI within large-scale GWAS meta-analysis of the GIANT consortium (n = 253.288)16 (Table 3). This evidence concerns the gene NTAN1 and type 2 diabetes mellitus.