Such association kept unchanged after further adjustment in model b, including smoking, AST/ALT, HDL, LDL, DBP, SBP, TG, TC, UA, physical activity, past history of CHD and hypertension (OR:1.30, 95% CI:1.07 to 1.59; OR: 1.46, 95% CI: 1.12 to 1.89). The gene discussed is GPT; the disease is Hypertension.