FLT3 and Miyoshi myopathy: An optimal cut-off value of FLT3-L (>92 pg/ml) was determined by the score closest to the value under peak sensitivity (FLT3-L: 70%) and specificity (FLT3-L: 71%), as a threshold to partition the MM patients into two groups: high bone marrow plasma levels of FLT3-L (FLT3-L >92 pg/ml) and low bone marrow plasma levels of FLT3-L (FLT3-L ≤92 pg/ml) (Fig 2B).