Arterial thrombosis (AT) were the most frequent APS-event (N = 25, 55% of APS events) and were mainly observed in patients in Group-1 (odds ratio 5.11, 95% CI: 1.73 to 15.13).Venous thrombosis were also more frequently observed in patients positive for IgA-aB2GP1 (odds ratio 4.76, 95% CI: 1.36 to 16.67; Table 2). This evidence concerns the gene CD79A and autoimmune polyendocrinopathy.