Magnolol treatment prevents sepsis-induced rat intestinal dysmotility by regulating stem cell factor (SCF)/c-kit and NO signaling to maintain functional interstitial cells of Cajal (ICCs) [21], reducing TNF-α and inducible nitric oxide synthase (iNOS), while stimulating IL-10 mRNA expression in septic rat ileum [22]. This evidence concerns the gene NOS2 and Sepsis.