PROM1 and cancer: In our previous work, we synthesised a series of 2-((benzimidazol-2-yl) thio)-1-arylethan-1-ones (Series 1, Figure 1) that proved to possess good anti-proliferative activity toward HT-29 colon cancer cell line besides its capability to inhibit cell surface expression of CD133 in HT-29 cancer cells.2