The UCHL1 levels in cerebrospinal fluid (CSF) and serum of rats have been found to significantly increase after 2‐hr or 6‐hr MCAO, but remain normal after haemorrhagic stroke, which indicate that UCHL1 may be a vital biomarker for cerebral ischaemia injury 22, 23. The gene discussed is UCHL1; the disease is hemorrhagic stroke.