Linked to this, 18F-fluorodeoxyglucose positron emission tomography (PET) has shown changes in Cer and Ctx connectivity patterns in relation to tremor in PD.130 DTI could also furnish information on the internal connectivity of areas, for example within the BG.131 At the micro-circuit and cellular level, data on dopamine production and receptors from PET and from dopamine transporter-single photon emission computed tomography (DAT-SPECT) could be used to set the model parameters so as to capture specific PD damages. The gene discussed is SLC6A3; the disease is Parkinson disease.