SNCA and Parkinson disease: In support, it was recently demonstrated that α-synuclein oligomers were present in neurons of PD patients prior to Lewy-body formation although a more sensitive detection method had to be developed to capture these oligomers.37 The similarity of the metabolomics data with that of PD patients strongly implies that FN075-injection promotes PD-like symptoms; this also gives indirect support for the involvement of α-synuclein.