Part of this well-orchestrated host innate response to stress or infection stimuli includes the release of small “danger signaling molecules” such as ATP which functions as a sensor against colonizing pathogens through activation of the purinergic receptor P2X7 (Gordon, 1986; Schwiebert and Zsembery, 2003; Trautmann, 2009; Yilmaz et al., 2010; Almeida-da-Silva et al., 2016). This evidence concerns the gene P2RX7 and infection.