TGFB1 and hepatocellular carcinoma: TGFβ is a signal for induction of EMT and is a frequent dysregulation in HCC.26,28 Here we set out to explore perturbations to the EMT signaling network that are predicted to increase the efficacy of SMAD complex inhibition (i.e., canonical TGFβ signaling) in order to inhibit the induction of EMT.