] study included 620 patients with diabetes and acute myocardial infarction (AMI) and used the following strategies: IV infusion of insulin and glucose in the first 24 h with a glycemic target of 126–196 mg/dL, subcutaneous administration of insulin four times daily for 3 months, vs. standard insulin therapy as clinically indicated at the time of the study. The gene discussed is INS; the disease is diabetes mellitus.