Such as, it was found at the cellular level, the upregulation of miR-126 in NSCLC A549 cells could reduce the expression of the target gene PIK3R2 and influence the PTEN/PI3K/AKT signaling pathway, suppressing the proliferation, migration, and invasive abilities of A549 cells [34]. The gene discussed is PTEN; the disease is non-small cell lung carcinoma.