Sequencing of other candidate genes affected in startle disease excluded further pathogenic sequence variations, as only common single nucleotide variants were found (Glrb: exon 5, c.A555G, p.L163L, rs13477223; SLC6A5: exon 2, c.A109G, p.T37A, rs31048165). This evidence concerns the gene SLC6A5 and hereditary hyperekplexia.