For instance, metastasis-associated lung adenocarcinoma transcript-1 (MALAT1) and lncRNA-activated by TGF-β (lncRNA-ATB) are upregulated in HCC tissues, while lncRNA low expression in tumor (lncRNA-LET) and lncRNA downregulated expression by HBx (lncRNA-Dreh) are downregulated in HCC. The gene discussed is MALAT1; the disease is hepatocellular carcinoma.