Markowitz et al. [29] validated DEPS-R in a pediatric sample of boys and girls with type 1 diabetes, obtaining a good internal consistency and good construct validity by means of comparison with areas that may be affected by the presence of a DEB (positive correlation with age, BMI standardized for age, sex and hemoglobin A1C), in addition to a good external validity based on clinicians’ reports of insulin restriction in their patients. This evidence concerns the gene INS and type 1 diabetes mellitus.