With respect to insulins, in the studied period, Conitec recommended that the SUS not incorporate both the long-acting insulin analogues glargine and detemir for the treatment of type 1 and 2 diabetes mellitus or the fast-acting insulin analogues lispro, aspart, and glulisine for the treatment of type 1 diabetes mellitus. This evidence concerns the gene INS and type 1 diabetes mellitus.