For example, Sensenbrenner syndrome (also known as cranioectodermal dysplasia [14]), a ciliopathy characterized by sagittal craniosynostosis with accompanying facial, skeletal, and ectodermal anomalies, is caused by mutations in the IFT-A genes IFT43 [15], WDR35 [16], IFT122 [17], WDR19 [18], and IFT140 [19]. The gene discussed is IFT140; the disease is cranioectodermal dysplasia.