MAP2K7 and lymphoma: While incubation with inhibitors of MAPK (SB203580 as an inhibitor of p38 MAPK and PD98059 as an inhibitor of MEK) had no significant effect on FDG uptake in all three lymphoma cell lines, inhibition of c-MYC (10058-F4), PI3K (LY294002) and mTOR (Rapamycin) led to a significant decrease in FDG uptake (Fig. 3).