T2D: type 2 diabetes; HDL: High Density Lipoprotein; LDL: Low Density Lipoprotein; eGFR: estimated Glomerular Filtration Rate; BMI: Body Mass Index; DPP-4: Dipeptidyl Peptidase 4; ACE: Angiotensin Converting Enzyme; ARB: Angiotensin Receptor Blocker. The gene discussed is DPP4; the disease is type 2 diabetes mellitus.