It would be useful to evaluate the palmitome in CSCs extracted from patients with different breast cancer subtypes and/or stages of disease; compare palmitoylation events between tumor and control samples; and assess the influence of estrogen, retinoid, and EGF signaling pathways on known palmitoylation-dependent proteins that regulate immune cells within the tumor microenvironment. The gene discussed is EGF; the disease is breast carcinoma.