Of the 15 patients, 10 had triple-negative breast cancer, 2 had estrogen receptor-positive disease, HER2-positive disease, 2 had estrogen receptor-positive disease, HER2-negative disease and 1 had estrogen receptor-negative disease, progesterone receptor-positive disease, and HER2-negative disease (Table 1). This evidence concerns the gene ESR1 and triple-negative breast carcinoma.