Fig. 2B, ATF4 in rat PCNsFig. 2D, LDH in rat PCNsFig. 3A,C, ATF4 in APPSwe PCNsFig. 6D, Anxiety-like behavior in PS19 miceFig. 6H, Fear-based learning and memory in PS19 miceFig. 7B, ATF4 in PS19 miceFig. 8C,D, P-tau by IHC in PS19 miceFig. 8F, CA1 pyramidal cell layer in PS19 miceFig. 10A,B, Locomotor activity in APPSwe miceFig. 10D, Fear-based retrieval in APPSwe mice. The gene discussed is MAPT; the disease is Anxiety.