Several neoplasms are reported in LRBA deficiency: Burkitt lymphoma [10], low-grade Ebstein Barr virus positive (EBV+) marginal zone lymphoma [17], lymphomatous central nervous system pseudotumor [2], dysplastic tubular adenoma and polyps [18], and immunoproliferative diseases [4, 7, 8], suggesting that proliferative diseases may present another feature of LRBA deficiency. This evidence concerns the gene LRBA and Burkitt lymphoma.