CD4 and ulcerative colitis: Similarly, the dynamic nature of gene expression regulation was also observed in dendritic cells stimulated with interferon‐γ,30 and in CD4+ T cells stimulated with anti‐CD3/anti‐CD28 beads.31 Ye et al. identified 157 GWAS SNPs that overlapped with genetic variants that affected gene expression in CD4+ T cells in a cohort of 348 healthy individuals.31 Notably, an ulcerative colitis variant nearby IL23R and a variant nearby IL2RA associated with T1D, MS and vitiligo, only presented an effect on gene expression 48 hr following stimulation.