For example, over 50% of CeD variants also expressed an eQTL effect.15 Disease‐associated variants affecting gene expression can point towards a dysregulated specific pathway, e.g. five of the inflammatory bowel disease (IBD) risk variants were also eQTLs that increased the expression levels of ITGA, ITGAL, ICAM and ITGB8 genes, encoding integrins, the pro‐inflammatory cell surface proteins that mediate leucocyte accumulation at the site of inflammation.16 This evidence concerns the gene ITGB8 and inflammatory bowel disease.