In the first paper on the myosin mesa (Spudich 2015), only ‘HCM mutations’ that are clearly causative of hypertrophic cardiomyopathy were included, as defined by large numbers of independent diseased individuals carrying that mutation and/or families showing co-segregation of phenotypic disease and the ‘HCM mutation’. The gene discussed is MYH14; the disease is hypertrophic cardiomyopathy.