Molecular studies were performed in eight of 11 patients with BL/DLBCL, and they showed the following abnormalities: monosomy 8 (n = 1), trisomy 8 (n = 1), t(8;14) (n = 1), no t(8;14) (n = 4), and an extra copy of c-Myc without t(8;14) rearrangement (n = 1). This evidence concerns the gene MYC and diffuse large B-cell lymphoma.